Recent publications
Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromes
June 1, 2022
Paracatu LC, Monlish DA, Greenberg ZJ, Fisher DAC, Walter MJ, Oh ST, Schuettpelz LG. Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromes. Exp Hematol. 2022 Jun;110:47-59. doi: 10.1016/j.exphem.2022.03.011. Epub 2022 Apr 1. PMID: 35367529.
Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice
October 19, 2021
TKrambs JR, Monlish DA, Gao F, Schuettpelz LG, Link DC. Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice. Front Immunol. 2021 Oct 19;12:767267. doi: 10.3389/fimmu.2021.767267. PMID: 34737755; PMCID: PMC8560790.D: PMC9046959.
Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study
April 1, 2022
Böhrer M, Fitzpatrick E, Hurley K, Xie J, Lee BE, Pang XL, Zhuo R, Parsons BD, Berenger BM, Chui L, Tarr PI, Ali S, Vanderkooi OG, Freedman SB; Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE), Pediatric Emergency Research Canada (PERC). Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study. Acad Emerg Med. 2022 Apr;29(4):429-441. doi: 10.1111/acem.14434. Epub 2022 Feb 8. PMID: 34962688.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
July 23, 2021
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. PMID: 34083450; PMCID: PMC8448524.
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
July 23, 2021
Cugurra A, Mamuladze T, Rustenhoven J, Dykstra T, Beroshvili G, Greenberg ZJ, Baker W, Papadopoulos Z, Drieu A, Blackburn S, Kanamori M, Brioschi S, Herz J, Schuettpelz LG, Colonna M, Smirnov I, Kipnis J. Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma. Science. 2021 Jul 23;373(6553):eabf7844. doi: 10.1126/science.abf7844. Epub 2021 Jun 3. PMID: 34083447; PMCID: PMC8863069.
Toll-Like Receptor Signaling in the Establishment and Function of the Immune System
June 2, 2021
Aluri J, Cooper MA, Schuettpelz LG. Toll-Like Receptor Signaling in the Establishment and Function of the Immune System. Cells. 2021 Jun 2;10(6):1374. doi: 10.3390/cells10061374. PMID: 34199501; PMCID: PMC8228919.
Open conformation of tetraspanins shapes interaction partner networks on cell membranes
September 15, 2020
Yang Y, Liu XR, Greenberg ZJ, Zhou F, He P, Fan L, Liu S, Shen G, Egawa T, Gross ML, Schuettpelz LG, Li W. Open conformation of tetraspanins shapes interaction partner networks on cell membranes. EMBO J. 2020 Sep 15;39(18):e105246. doi: 10.15252/embj.2020105246. Epub 2020 Aug 16. PMID: 32974937; PMCID: PMC7507038.
TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS
August 1, 2020
Monlish DA, Greenberg ZJ, Bhatt ST, Leonard KM, Romine MP, Dong Q, Bendesky L, Duncavage EJ, Magee JA, Schuettpelz LG. TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS. Exp Hematol. 2020 Aug;88:42-55. doi: 10.1016/j.exphem.2020.07.001. Epub 2020 Jul 8. PMID: 32652111; PMCID: PMC7673652.
Recent publications
- Cutting Edge: The Tetraspanin CD53 Promotes CXCR4 Signaling and Bone Marrow Homing in B CellsChakraborty, M., Greenberg, Z. J., Dong, Q., Roundy, N., Bednarski, J. J., Paracatu, L. C., Duncavage, E., Li, W. & Schuettpelz, L. G., Apr 1 2024, In: Journal of Immunology. 212, 7, p. 1075-1080 6 p.Research output: Contribution to journal › Article › peer-review
- Acute disseminated encephalomyelitis as paraneoplastic syndrome preceding pediatric B acute lymphoblastic leukemiaLakshmi Narasimhan, M., Wilson, D. B. & Schuettpelz, L. G., 2024, (Accepted/In press) In: Pediatric Blood and Cancer.Research output: Contribution to journal › Letter › peer-review
- Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entryYang, F., Suo, M., Weli, H., Wong, M., Junidi, A., Cummings, C., Johnson, R., Mallory, K., Liu, A. Y., Greenberg, Z. J., Schuettpelz, L. G., Miller, M. J., Luke, C. J., Randolph, G. J., Zinselmeyer, B. H., Wardenburg, J. B. & Clemens, R. A., Nov 28 2023, In: Cell Reports. 42, 11, 113394.Research output: Contribution to journal › Article › peer-review
- Idiopathic multicentric Castleman disease in an adolescent diagnosed following COVID-19 infectionMosleh, E., Mehta, S., Young, E., Zhang, L., Vij, K. & Schuettpelz, L. G., Jun 2023, In: Pediatric Blood and Cancer. 70, 6, e30239.Research output: Contribution to journal › Letter › peer-review
- NADPH oxidase 2 limits amplification of IL-1β–G-CSF axis and an immature neutrophil subset in murine lung inflammationSong, Z., Bhattacharya, S., Huang, G., Greenberg, Z. J., Yang, W., Bagaitkar, J., Schuettpelz, L. G. & Dinauer, M. C., Apr 11 2023, In: Blood Advances. 7, 7, p. 1225-1240 16 p.Research output: Contribution to journal › Article › peer-review
- The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescenceGreenberg, Z. J., Paracatu, L. C., Monlish, D. A., Dong, Q., Rettig, M., Roundy, N., Gaballa, R., Li, W., Yang, W., Luke, C. J. & Schuettpelz, L. G., Mar 9 2023, In: Blood. 141, 10, p. 1180-1193 14 p.Research output: Contribution to journal › Article › peer-review
- The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytesHiggins, C. B., Adams, J. A., Ward, M. H., Greenberg, Z. J., Milewska, M., Sun, J., Zhang, Y., Chiquetto Paracatu, L., Dong, Q., Ballentine, S., Li, W., Wandzik, I., Schuettpelz, L. G. & DeBosch, B. J., Feb 2023, In: Journal of Biological Chemistry. 299, 2, 102835.Research output: Contribution to journal › Article › peer-review
- Editorial: Updates on toll-like receptors in cancer immunity and immunotherapyHoden, B., Nagai, Y., Schuettpelz, L. & Zhang, D., 2023, In: Frontiers in immunology. 14, 1331317.Research output: Contribution to journal › Editorial
- A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in miceSchmitt, E. G., Toth, K. A., Risma, S. I., Kolicheski, A., Saucier, N., Feliciano Berríos, R. J., Greenberg, Z. J., Leiding, J. W., Bleesing, J. J., Thatayatikom, A., Schuettpelz, L. G., Edwards, J. R., Vogel, T. P. & Cooper, M. A., Nov 8 2022, In: JCI Insight. 7, 21, e162695.Research output: Contribution to journal › Article › peer-review
- Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromesParacatu, L. C., Monlish, D. A., Greenberg, Z. J., Fisher, D. A. C., Walter, M. J., Oh, S. T. & Schuettpelz, L. G., Jun 2022, In: Experimental Hematology. 110, p. 47-59 13 p.Research output: Contribution to journal › Article › peer-review