Publications

Recent publications

Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromes

June 1, 2022

Paracatu LC, Monlish DA, Greenberg ZJ, Fisher DAC, Walter MJ, Oh ST, Schuettpelz LG. Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromes. Exp Hematol. 2022 Jun;110:47-59. doi: 10.1016/j.exphem.2022.03.011. Epub 2022 Apr 1. PMID: 35367529.

Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice

October 19, 2021

TKrambs JR, Monlish DA, Gao F, Schuettpelz LG, Link DC. Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice. Front Immunol. 2021 Oct 19;12:767267. doi: 10.3389/fimmu.2021.767267. PMID: 34737755; PMCID: PMC8560790.D: PMC9046959.

Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study

April 1, 2022

Böhrer M, Fitzpatrick E, Hurley K, Xie J, Lee BE, Pang XL, Zhuo R, Parsons BD, Berenger BM, Chui L, Tarr PI, Ali S, Vanderkooi OG, Freedman SB; Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE), Pediatric Emergency Research Canada (PERC). Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study. Acad Emerg Med. 2022 Apr;29(4):429-441. doi: 10.1111/acem.14434. Epub 2022 Feb 8. PMID: 34962688.

Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders

July 23, 2021

Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. PMID: 34083450; PMCID: PMC8448524.

Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma

July 23, 2021

Cugurra A, Mamuladze T, Rustenhoven J, Dykstra T, Beroshvili G, Greenberg ZJ, Baker W, Papadopoulos Z, Drieu A, Blackburn S, Kanamori M, Brioschi S, Herz J, Schuettpelz LG, Colonna M, Smirnov I, Kipnis J. Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma. Science. 2021 Jul 23;373(6553):eabf7844. doi: 10.1126/science.abf7844. Epub 2021 Jun 3. PMID: 34083447; PMCID: PMC8863069.

Toll-Like Receptor Signaling in the Establishment and Function of the Immune System

June 2, 2021

Aluri J, Cooper MA, Schuettpelz LG. Toll-Like Receptor Signaling in the Establishment and Function of the Immune System. Cells. 2021 Jun 2;10(6):1374. doi: 10.3390/cells10061374. PMID: 34199501; PMCID: PMC8228919.

Open conformation of tetraspanins shapes interaction partner networks on cell membranes

September 15, 2020

Yang Y, Liu XR, Greenberg ZJ, Zhou F, He P, Fan L, Liu S, Shen G, Egawa T, Gross ML, Schuettpelz LG, Li W. Open conformation of tetraspanins shapes interaction partner networks on cell membranes. EMBO J. 2020 Sep 15;39(18):e105246. doi: 10.15252/embj.2020105246. Epub 2020 Aug 16. PMID: 32974937; PMCID: PMC7507038.

TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS

August 1, 2020

Monlish DA, Greenberg ZJ, Bhatt ST, Leonard KM, Romine MP, Dong Q, Bendesky L, Duncavage EJ, Magee JA, Schuettpelz LG. TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS. Exp Hematol. 2020 Aug;88:42-55. doi: 10.1016/j.exphem.2020.07.001. Epub 2020 Jul 8. PMID: 32652111; PMCID: PMC7673652.

Recent publications

• A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice
  August 5, 2024
  A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in miceToth, K. A., Schmitt, E. G., Kolicheski, A., Greenberg, Z. J., Levendosky, E., Saucier, N., Trammel, K., Oikonomou, V., Lionakis, M. S., Klechevsky, E., Kim, B. S., Schuettpelz, L. G., Saligrama, N. & Cooper, M. A., Aug 5 2024, In: Journal of Experimental Medicine. 221, 8, e20232091.Research output: Contribution to journal › Article › peer-review
• Acute disseminated encephalomyelitis as paraneoplastic syndrome preceding pediatric B acute lymphoblastic leukemia
  June 1, 2024
  Acute disseminated encephalomyelitis as paraneoplastic syndrome preceding pediatric B acute lymphoblastic leukemiaLakshmi Narasimhan, M., Wilson, D. & Schuettpelz, L. G., Jun 2024, In: Pediatric Blood and Cancer. 71, 6, e30967.Research output: Contribution to journal › Letter › peer-review
• Cutting Edge: The Tetraspanin CD53 Promotes CXCR4 Signaling and Bone Marrow Homing in B Cells
  April 1, 2024
  Cutting Edge: The Tetraspanin CD53 Promotes CXCR4 Signaling and Bone Marrow Homing in B CellsChakraborty, M., Greenberg, Z. J., Dong, Q., Roundy, N., Bednarski, J. J., Paracatu, L. C., Duncavage, E., Li, W. & Schuettpelz, L. G., Apr 1 2024, In: Journal of Immunology. 212, 7, p. 1075-1080 6 p.Research output: Contribution to journal › Article › peer-review
• Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entry
  November 28, 2023
  Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entryYang, F., Suo, M., Weli, H., Wong, M., Junidi, A., Cummings, C., Johnson, R., Mallory, K., Liu, A. Y., Greenberg, Z. J., Schuettpelz, L. G., Miller, M. J., Luke, C. J., Randolph, G. J., Zinselmeyer, B. H., Wardenburg, J. B. & Clemens, R. A., Nov 28 2023, In: Cell Reports. 42, 11, 113394.Research output: Contribution to journal › Article › peer-review
• Idiopathic multicentric Castleman disease in an adolescent diagnosed following COVID-19 infection
  June 1, 2023
  Idiopathic multicentric Castleman disease in an adolescent diagnosed following COVID-19 infectionMosleh, E., Mehta, S., Young, E., Zhang, L., Vij, K. & Schuettpelz, L. G., Jun 2023, In: Pediatric Blood and Cancer. 70, 6, e30239.Research output: Contribution to journal › Letter › peer-review
• NADPH oxidase 2 limits amplification of IL-1β–G-CSF axis and an immature neutrophil subset in murine lung inflammation
  April 11, 2023
  NADPH oxidase 2 limits amplification of IL-1β–G-CSF axis and an immature neutrophil subset in murine lung inflammationSong, Z., Bhattacharya, S., Huang, G., Greenberg, Z. J., Yang, W., Bagaitkar, J., Schuettpelz, L. G. & Dinauer, M. C., Apr 11 2023, In: Blood Advances. 7, 7, p. 1225-1240 16 p.Research output: Contribution to journal › Article › peer-review
• The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescence
  March 9, 2023
  The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescenceGreenberg, Z. J., Paracatu, L. C., Monlish, D. A., Dong, Q., Rettig, M., Roundy, N., Gaballa, R., Li, W., Yang, W., Luke, C. J. & Schuettpelz, L. G., Mar 9 2023, In: Blood. 141, 10, p. 1180-1193 14 p.Research output: Contribution to journal › Article › peer-review
• The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes
  February 1, 2023
  The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytesHiggins, C. B., Adams, J. A., Ward, M. H., Greenberg, Z. J., Milewska, M., Sun, J., Zhang, Y., Chiquetto Paracatu, L., Dong, Q., Ballentine, S., Li, W., Wandzik, I., Schuettpelz, L. G. & DeBosch, B. J., Feb 2023, In: Journal of Biological Chemistry. 299, 2, 102835.Research output: Contribution to journal › Article › peer-review
• Editorial: Updates on toll-like receptors in cancer immunity and immunotherapy
  January 1, 2023
  Editorial: Updates on toll-like receptors in cancer immunity and immunotherapyHoden, B., Nagai, Y., Schuettpelz, L. & Zhang, D., 2023, In: Frontiers in immunology. 14, 1331317.Research output: Contribution to journal › Editorial
• A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice
  November 8, 2022
  A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in miceSchmitt, E. G., Toth, K. A., Risma, S. I., Kolicheski, A., Saucier, N., Feliciano Berríos, R. J., Greenberg, Z. J., Leiding, J. W., Bleesing, J. J., Thatayatikom, A., Schuettpelz, L. G., Edwards, J. R., Vogel, T. P. & Cooper, M. A., Nov 8 2022, In: JCI Insight. 7, 21, e162695.Research output: Contribution to journal › Article › peer-review